A NIGHT OF CONFESSIONS; THE EPIC SUPERHERO CROSSOVER KICKS OFF — Eliza (guest star Helen Slater) comes to town to celebrate Thanksgiving with her daughters. Alex (Chyler Leigh) decides it’s time to come out to her mother; Kara (Melisa Benoist) is shocked when Eliza suggests Mon-El (Chris Wood) has feelings for her, and Winn (Jeremy Jordan) and James (Mehcad Brooks) consider telling Kara the truth about the Guardian. Meanwhile, CADMUS unleashes a virus that instantly kills any alien in the vicinity so Kara enlists an unexpected ally – Lena Luthor (Katie McGrath). The epic superhero crossover kicks off tonight when Barry Allen (guest star Grant Gustin) and Cisco Ramon (guest star Carlos Valdes) seek Kara’s help with an alien invasion on their Earth.
Kara Zor-El escapes doom on planet Krypton to find protection on Earth with the Danver family, where she grows up in the shadow of her foster sister, Alex, and learns to hide the extraordinary powers she shares with her cousin, SupermanMercy Street
Follows the lives of two volunteer nurses on opposing sides of the Civil War - New England abolitionist Mary Phinney and Confederate supporter Emma Green